5. Extreme Fatigue
Extreme fatigue is a common symptom of many types of bacterial infection. As such, experiencing fatigue on its own is not necessarily a sign of syphilis. Extreme fatigue experienced after the initial sore, though, does make a syphilis infection more likely. It is important to note that this type of fatigue does not come after extreme physical exertion, but rather can strike at any time. As such, fatigue experienced without a logical reason should be looked at as part of a possible infection.
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